Our laboratory studies the cellular and molecular mechanisms governing heart generation and regeneration. In particular, we are interested in understanding the fundamental biology and regenerative potential of cardiac progenitor cells – building blocks used to form the heart during fetal development. We are also interested in elucidating the maturation event of heart muscle cells, an essential process to generate adult cardiomyocytes, which occurs after terminal differentiation of the progenitor cells. We believe this knowledge will contribute to our understanding of congenital and adult heart disease and be instrumental for stem cell-based heart regeneration.
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HEART GENERATION AND REGENERATION
CHULAN KWON LABORATORY